{"id":3495,"date":"2016-03-16T16:27:12","date_gmt":"2016-03-16T14:27:12","guid":{"rendered":"http:\/\/www.genomed-biotech.com\/?post_type=portfolio&#038;p=3495"},"modified":"2016-03-29T10:12:33","modified_gmt":"2016-03-29T07:12:33","slug":"y-chromosome-microdeletion-detection-kit","status":"publish","type":"portfolio","link":"http:\/\/www.genomed-biotech.com\/index.php\/products\/y-chromosome-microdeletion-detection-kit\/","title":{"rendered":"Y Chromosome Microdeletion Detection Kit"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_image-b52bba447d0631aaa6e8d2a542633df8\">\n.avia-image-container.av-av_image-b52bba447d0631aaa6e8d2a542633df8 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-av_image-b52bba447d0631aaa6e8d2a542633df8 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-av_image-b52bba447d0631aaa6e8d2a542633df8 av-styling- avia-align-center  avia-builder-el-0  el_before_av_two_third  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-3482 avia-img-lazy-loading-not-3482 avia_image ' src=\"http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/young-couple-at-gynecological-office-1500x630.jpg\" alt='' title='Young couple at gynecological office'  height=\"630\" width=\"1500\"  itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_two_third-9497bbf8bff73ea4c6992cc17fa9ec36\">\n.flex_column.av-av_two_third-9497bbf8bff73ea4c6992cc17fa9ec36{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_two_third-9497bbf8bff73ea4c6992cc17fa9ec36 av_two_third  avia-builder-el-1  el_after_av_image  el_before_av_one_third  first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: justify;\">Microdeletions of the Y chromosome are the second most frequent genetic cause of spermatogenetic failure in infertile men after the Klinefelter syndrome (47, XXY). The molecular diagnosis of Y chromosomal microdeletions is routinely performed in the workup of male infertility in men with azoospermia or severe oligozoospermia.<\/p>\n<p style=\"text-align: justify;\">The portion of the male-specific region of the Y chromosome (MSY), comprising 95% of the Y chromosome and flanked by pseudoautosomal regions which is affected by deletions, has been classically subdivided into four regions called AZFa, AZFb, AZFc and proximal AZFc (AZFd), respectively.<\/p>\n<\/div><\/section><br \/>\n<div  class='tabcontainer av-av_tab_container-0bacd910096d11a3cec6dfb538798966 top_tab  avia-builder-el-3  el_after_av_textblock  avia-builder-el-last '>\n<section class='av_tab_section av_tab_section av-av_tab-618106d451774598763fabd963d4a3bc'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-1-tab' class='tab active_tab' role='tab' aria-selected=\"true\" tabindex=\"0\" data-fake-id='#tab-id-1' aria-controls='tab-id-1-content'  itemprop=\"headline\" >Product Overview<\/div><div id='tab-id-1-content' class='tab_content active_tab_content' role='tabpanel' aria-labelledby='tab-id-1-tab' aria-hidden=\"false\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-3488 size-medium\" src=\"http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel1-300x116.png\" alt=\"ydel1\" width=\"300\" height=\"116\" srcset=\"http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel1-300x116.png 300w, http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel1-705x273.png 705w, http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel1-450x174.png 450w, http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel1.png 761w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>This system consists of 14 primer pairs that are homologous to previously identified and mapped sequence-tagged sites (STSs). Y chromosome deletions in the regions that are amplified by these primer sets have been associated with male infertility. This system uses a five-dye fluorescent system for automated DNA fragment analysis, which allows multiplex amplification and electrophoresis of over 14 STSs which include AMXY marker (Chr.X: 104bp, Chr.Y: 109bp; Xp22.1, Yp11.2) simultaneously. The kit is intended for use on Applied Biosystems ABI PRISM<sup>\u00ae<\/sup> genetic analyzers.<\/p>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel2.png\" rel=\"attachment wp-att-3489\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-gallery wp-image-3489\" src=\"http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel2-845x684.png\" alt=\"ydel2\" width=\"845\" height=\"684\" srcset=\"http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel2-845x684.png 845w, http:\/\/www.genomed-biotech.com\/wp-content\/uploads\/2016\/03\/ydel2-495x400.png 495w\" sizes=\"auto, (max-width: 845px) 100vw, 845px\" \/><\/a><\/p>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-av_tab-e9d41cb7a1df35f8a2a6e2d96ed1eeb2'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-2-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-2' aria-controls='tab-id-2-content'  itemprop=\"headline\" >Main Features<\/div><div id='tab-id-2-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-2-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><ul>\n<li>Contains all necessary reagents for the amplification of human genomic DNA<\/li>\n<li>Relative quantification between Chr.X and Chr.Y (AMXY marker) allows the pre-assessment of possible Klinefelter syndrome<\/li>\n<li>A human male DNA used as external control to check DNA integrity and PCR inhibitors as well as performance of reagents in the kit<\/li>\n<li>Precise and quick detection for all STSs in the same plot screen<\/li>\n<li>Coverage of the maximum number of possible Y chromosome microdeletions<\/li>\n<li>Contains all 6 markers determined by European Molecular Genetics Quality Network guidelines<\/li>\n<li>SRY is a control marker for the testis determining factor on the short arm of the\u00a0 chromosome and allows XX males arising from Y to X translocations to be detected.<\/li>\n<\/ul>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-av_tab-ea1c6b29a588693cb336629ac3f00720'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-3-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-3' aria-controls='tab-id-3-content'  itemprop=\"headline\" >Order Information<\/div><div id='tab-id-3-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-3-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><table class=\"avia-table avia-data-table avia-table-4 avia-builder-el-12 el_after_av_table avia-builder-el-last \">\n<tbody>\n<tr class=\"avia-heading-row\">\n<th class=\"\">Cat. No<\/th>\n<th class=\"\">Description<\/th>\n<\/tr>\n<tr class=\"\">\n<td class=\"\">206100<\/td>\n<td class=\"\">100 tests<\/td>\n<\/tr>\n<tr class=\"\">\n<td class=\"\">206050<\/td>\n<td class=\"\">50 tests<\/td>\n<\/tr>\n<tr class=\"\">\n<td class=\"\">206025<\/td>\n<td class=\"\">25 tests<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><\/div><\/section>\n<section class='av_tab_section av_tab_section av-av_tab-65d033b3e2bbecbbcd984a41b2018c77'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div id='tab-id-4-tab' class='tab' role='tab' aria-selected=\"false\" tabindex=\"0\" data-fake-id='#tab-id-4' aria-controls='tab-id-4-content'  itemprop=\"headline\" >Product Support<\/div><div id='tab-id-4-content' class='tab_content' role='tabpanel' aria-labelledby='tab-id-4-tab' aria-hidden=\"true\"><div class='tab_inner_content invers-color'  itemprop=\"text\" ><p>Please email us for product support requests\u00a0and include your product LOT number.<\/p>\n<p>Support e-mail:\u00a0<a href=\"mailto:support@genomed-biotech.com\">support@genomed-biotech.com<\/a><\/p>\n<\/div><\/div><\/section>\n<\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_third-9c1d454dc06f7247226bc4e8f931daae\">\n.flex_column.av-av_one_third-9c1d454dc06f7247226bc4e8f931daae{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_one_third-9c1d454dc06f7247226bc4e8f931daae av_one_third  avia-builder-el-4  el_after_av_two_third  avia-builder-el-last  flex_column_div av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_hr-c9ba6ccf0e28539cef079a4b419f7f68\">\n#top .hr.hr-invisible.av-av_hr-c9ba6ccf0e28539cef079a4b419f7f68{\nheight:25px;\n}\n<\/style>\n<div  class='hr av-av_hr-c9ba6ccf0e28539cef079a4b419f7f68 hr-invisible  avia-builder-el-5  el_before_av_icon_box  avia-builder-el-first '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<article  class='iconbox iconbox_top av-av_icon_box-447b64b5e12939110154236a3f635623  avia-builder-el-6  el_after_av_hr  el_before_av_icon_box  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: Sample\"><div class=\"iconbox_icon heading-color\" aria-hidden='true' data-av_icon='\ue89a' data-av_iconfont='entypo-fontello'><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >Sample<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><br \/>\n<article  class='iconbox iconbox_top av-av_icon_box-03d7fc102b1fb957cd8496bd6fea7b6b  avia-builder-el-7  el_after_av_icon_box  el_before_av_icon_box  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: DNA Extraction\"><div class=\"iconbox_icon heading-color\" aria-hidden='true' data-av_icon='\ue887' data-av_iconfont='entypo-fontello'><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >DNA Extraction<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><p>20 min.<\/p>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><br \/>\n<article  class='iconbox iconbox_top av-av_icon_box-18312f72a2ca2ad21c4799e1d24dced1  avia-builder-el-8  el_after_av_icon_box  el_before_av_icon_box  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: QF-PCR Amplification\"><div class=\"iconbox_icon heading-color\" aria-hidden='true' data-av_icon='\ue887' data-av_iconfont='entypo-fontello'><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >QF-PCR Amplification<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><p>120 min.<\/p>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><br \/>\n<article  class='iconbox iconbox_top av-av_icon_box-0fed0ed0f151cb1440d9f4bf0c0b3813  avia-builder-el-9  el_after_av_icon_box  el_before_av_icon_box  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: Electrophoresis - Analysis\"><div class=\"iconbox_icon heading-color\" aria-hidden='true' data-av_icon='\ue887' data-av_iconfont='entypo-fontello'><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >Electrophoresis - Analysis<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><p>30 min.<\/p>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><br \/>\n<article  class='iconbox iconbox_top av-av_icon_box-4a50bd3b7764402d51ab1cfa9558f0b1  avia-builder-el-10  el_after_av_icon_box  avia-builder-el-last  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: Result\"><div class=\"iconbox_icon heading-color\" aria-hidden='true' data-av_icon='\ue887' data-av_iconfont='entypo-fontello'><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >Result<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/p><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":3482,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"portfolio_entries":[34],"class_list":["post-3495","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry","portfolio_entries-diagnostic-kits"],"_links":{"self":[{"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/portfolio\/3495","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/types\/portfolio"}],"author":[{"embeddable":true,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/comments?post=3495"}],"version-history":[{"count":1,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/portfolio\/3495\/revisions"}],"predecessor-version":[{"id":3507,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/portfolio\/3495\/revisions\/3507"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/media\/3482"}],"wp:attachment":[{"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/media?parent=3495"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/tags?post=3495"},{"taxonomy":"portfolio_entries","embeddable":true,"href":"http:\/\/www.genomed-biotech.com\/index.php\/wp-json\/wp\/v2\/portfolio_entries?post=3495"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}